Interleukin-7 (IL-7) is required, and limiting, for T-cell development and survival. IL-7 production by stromal cells in lymphoid tissues is constitutive. The amount of available IL-7 is proposed to ...
A major class of tumors lack expression of the transporters associated with antigen processing (TAP). These proteins are essential for delivery of antigenic peptides into the lumen of the endoplasmic ...
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